May 8 2013

Americord Cord Blood Processing, What is our Process?

Posted by Martin Smithmyer

We often get questions from clients who want to know more about our cord blood process and how we compare to other banks.  Some cord blood banks store collections without separating the part of the collection that contains stem cells; this is not the best method. When cord blood arrives at our laboratory it is separated by weight via centrifugation. The part of cord blood that contains stem cells is called the buffy coat and it also contains white blood cells. The rest of the cord blood contains a combination of plasma and red blood cells which are not used in the treatment of diseases. This separation accomplishes two things, it makes the collection easier to use after being thawed because it will no longer require the separation of the cells at a later time.  It also allows a smaller concentration of the cryoprotectant agent that can be toxic in high quantities. We go a step further and separate the collection into a bag with 2 integral segments. The bag contains a majority of the collection. The two attached segments are smaller volumes to be used for HLA testing, which is usually done when the collection is being considered for a medical therapy.

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