--- title: FDA-Approved Cord Blood Treatments date: 2023-08-12T19:36:00-04:00 author: John Henry Donovan canonical_url: "https://www.americordblood.com/fda-approved-treatments" section: How it Works --- # FDA-Approved Cord Blood Treatments Cord blood stem cells are the key to unlocking a brighter and healthier future. Today’s treatment possibilities range from cancers to metabolic, immune, and blood disorders. However, active research in numerous clinical trials is constantly being done to make way for new treatment opportunities. ![Smiling african americord baby americord](https://assets.americordblood.com/transforms/heroimages/85230/smiling-african-americord-baby-americord_cb1126afb0aaa502bb960de8f9d7f592.jpg) ![Smiling african americord baby americord](https://assets.americordblood.com/transforms/heroimages/85230/smiling-african-americord-baby-americord_49a639b762324ba7a416856899a48542.jpg) ## **FDA-Approved** Cord Blood Treatments There are now over 80 medical conditions that can be treated with the hematopoietic stem cells (HSCs) collected from cord blood. For some diseases, these treatments are the only therapy, and in other diseases, they are only employed when front-line therapies have failed or the disease is very aggressive. In the United States, most health insurance providers will pay for a stem cell transplant if it is a "standard therapy" for the patient's diagnosis. ### Cancers ### Leukemias (a cancer of the blood immune system, where the cells are called leukocytes or white cells) Autologous(Used by baby) Acute Biphenotypic Leukemia Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Acute Undifferentiated Leukemia Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Juvenile Chronic Myelogenous Leukemia (JCML) Juvenile Myelomonocytic Leukemia (JMML) Allogeneic(Used by sibling or family) Acute Biphenotypic Leukemia Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Acute Undifferentiated Leukemia Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Juvenile Chronic Myelogenous Leukemia (JCML) Juvenile Myelomonocytic Leukemia (JMML) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Acute Biphenotypic Leukemia Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Acute Undifferentiated Leukemia Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Juvenile Chronic Myelogenous Leukemia (JCML) Juvenile Myelomonocytic Leukemia (JMML) ### Myelodysplastic Syndromes (also called pre-leukemia) Autologous(Used by baby) Refractory Anemia Refractory Anemia with Ringed Sideroblasts Refractory Anemia with Excess Blasts Refractory Anemia with Excess Blasts in Transformation Chronic Myelomonocytic Leukemia (CMML) Allogeneic(Used by sibling or family) Refractory Anemia Refractory Anemia with Ringed Sideroblasts Refractory Anemia with Excess Blasts Refractory Anemia with Excess Blasts in Transformation Chronic Myelomonocytic Leukemia (CMML) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Refractory Anemia Refractory Anemia with Ringed Sideroblasts Refractory Anemia with Excess Blasts Refractory Anemia with Excess Blasts in Transformation Chronic Myelomonocytic Leukemia (CMML) ### Lymphomas (a cancer of the blood immune system, where the cells are called leukocytes or white cells) Autologous(Used by baby) Hodgkin’s Lymphoma Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma) Allogeneic(Used by sibling or family) Hodgkin’s Lymphoma Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Hodgkin’s Lymphoma Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma) ### Solid Tumors (not originating in the blood or immune system) Autologous(Used by baby) Neuroblastoma Retinoblastoma Medulloblastoma Allogeneic(Used by sibling or family) Neuroblastoma Retinoblastoma Medulloblastoma Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Neuroblastoma Retinoblastoma Medulloblastoma ### Blood Disorders ### Anemias (deficiencies or malformations of red cells) Autologous(Used by baby) Aplastic Anemia Congenital Dyserythropoietic Anemia Fanconi Anemia Paroxysmal Nocturnal Hemoglobinuria (PNH) Allogeneic(Used by sibling or family) Aplastic Anemia Congenital Dyserythropoietic Anemia Fanconi Anemia Paroxysmal Nocturnal Hemoglobinuria (PNH) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Aplastic Anemia Congenital Dyserythropoietic Anemia Fanconi Anemia Paroxysmal Nocturnal Hemoglobinuria (PNH) ### Inherited Red Cell (Erythrocyte) Abnormalities (red cells contain hemoglobin and carry oxygen to the body) Autologous(Used by baby) Beta Thalassemia Major (also known as Cooley’s Anemia) Diamond-Blackfan Anemia Pure Red Cell Aplasia Sickle Cell Disease Allogeneic(Used by sibling or family) Beta Thalassemia Major (also known as Cooley’s Anemia) Diamond-Blackfan Anemia Pure Red Cell Aplasia Sickle Cell Disease Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Beta Thalassemia Major (also known as Cooley’s Anemia) Diamond-Blackfan Anemia Pure Red Cell Aplasia Sickle Cell Disease ### Inherited Platelet Anomalies (platelets are blood cells needed for clotting) Autologous(Used by baby) Amegakaryocytosis / Congenital Thrombocytopenia Glanzmann Thrombasthenia Allogeneic(Used by sibling or family) Amegakaryocytosis / Congenital Thrombocytopenia Glanzmann Thrombasthenia Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Amegakaryocytosis / Congenital Thrombocytopenia Glanzmann Thrombasthenia ### Inherited Immune System Disorders: Severe Combined Immunodeficiency (SCID) Autologous(Used by baby) SCID with Adenosine Deaminase Deficiency(ADA-SCID) SCID which is X-linked SCID with absence of T & B Cells SCID with absence of T Cells, Normal B Cells Omenn Syndrome Allogeneic(Used by sibling or family) SCID with Adenosine Deaminase Deficiency(ADA-SCID) SCID which is X-linked SCID with absence of T & B Cells SCID with absence of T Cells, Normal B Cells Omenn Syndrome Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) SCID with Adenosine Deaminase Deficiency(ADA-SCID) SCID which is X-linked SCID with absence of T & B Cells SCID with absence of T Cells, Normal B Cells Omenn Syndrome ### Inherited Immune System Disorders: Neutropenias Autologous(Used by baby) Infantile Genetic Agranulocytosis (Kostmann Syndrome) Myelokathexis Allogeneic(Used by sibling or family) Infantile Genetic Agranulocytosis (Kostmann Syndrome) Myelokathexis Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Infantile Genetic Agranulocytosis (Kostmann Syndrome) Myelokathexis ### Inherited Immune System Disorders–Other Autologous(Used by baby) Ataxia-Telangiectasia Bare Lymphocyte Syndrome Common Variable Immunodeficiency DiGeorge Syndrome Leukocyte Adhesion Deficiency Lymphoproliferative Disorders Lymphoproliferative Disorder, X-linked (also known as Epstein-Barr Virus Susceptibility) Wiskott-Aldrich Syndrome Allogeneic(Used by sibling or family) Ataxia-Telangiectasia Bare Lymphocyte Syndrome Common Variable Immunodeficiency DiGeorge Syndrome Leukocyte Adhesion Deficiency Lymphoproliferative Disorders Lymphoproliferative Disorder, X-linked (also known as Epstein-Barr Virus Susceptibility) Wiskott-Aldrich Syndrome Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Ataxia-Telangiectasia Bare Lymphocyte Syndrome Common Variable Immunodeficiency DiGeorge Syndrome Leukocyte Adhesion Deficiency Lymphoproliferative Disorders Lymphoproliferative Disorder, X-linked (also known as Epstein-Barr Virus Susceptibility) Wiskott-Aldrich Syndrome ### Myeloproliferative Disorders Autologous(Used by baby) Acute Myelofibrosis Agnogenic Myeloid Metaplasia (Myelofibrosis) Polycythemia Vera Essential Thrombocythemia Allogeneic(Used by sibling or family) Acute Myelofibrosis Agnogenic Myeloid Metaplasia (Myelofibrosis) Polycythemia Vera Essential Thrombocythemia Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Acute Myelofibrosis Agnogenic Myeloid Metaplasia (Myelofibrosis) Polycythemia Vera Essential Thrombocythemia ### Phagocyte Disorders Autologous(Used by baby) Chediak-Higashi Syndrome Chronic Granulomatous Disease Neutrophil Actin Deficiency Reticular Dysgenesis Allogeneic(Used by sibling or family) Chediak-Higashi Syndrome Chronic Granulomatous Disease Neutrophil Actin Deficiency Reticular Dysgenesis Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Chediak-Higashi Syndrome Chronic Granulomatous Disease Neutrophil Actin Deficiency Reticular Dysgenesis ### Cancers in the Bone Marrow Autologous(Used by baby) Multiple Myeloma Primary Plasma Cell Leukemia (PCL) Secondary Plasma Cell Leukemia Waldenstrom’s Macroglobulinemia Allogeneic(Used by sibling or family) Multiple Myeloma Primary Plasma Cell Leukemia (PCL) Secondary Plasma Cell Leukemia Waldenstrom’s Macroglobulinemia Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Multiple Myeloma Primary Plasma Cell Leukemia (PCL) Secondary Plasma Cell Leukemia Waldenstrom’s Macroglobulinemia ### Immune Disorders ### Inherited Disorders (immune system and other organs) Autologous(Used by baby) Cartilage-Hair Hypoplasia Gunther’s Disease (Erythropoietic Porphyria) Hermansky-Pudlak Syndrome Pearson’s Syndrome Shwachman-Diamond Syndrome Systemic Mastocytosis Allogeneic(Used by sibling or family) Cartilage-Hair Hypoplasia Gunther’s Disease (Erythropoietic Porphyria) Hermansky-Pudlak Syndrome Pearson’s Syndrome Shwachman-Diamond Syndrome Systemic Mastocytosis Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Cartilage-Hair Hypoplasia Gunther’s Disease (Erythropoietic Porphyria) Hermansky-Pudlak Syndrome Pearson’s Syndrome Shwachman-Diamond Syndrome Systemic Mastocytosis ### Metabolic Disorders ### Mucopolysaccharidosis (MPS) Storage Diseases Autologous(Used by baby) Hunter Syndrome (MPS-II) Hurler Syndrome (MPS-IH) Maroteaux-Lamy Syndrome (MPS-VI) Morquio Syndrome (MPS-IV) Sanfilippo Syndrome (MPS-III) Scheie Syndrome (MPS-IS) Allogeneic(Used by sibling or family) Hunter Syndrome (MPS-II) Hurler Syndrome (MPS-IH) Maroteaux-Lamy Syndrome (MPS-VI) Morquio Syndrome (MPS-IV) Sanfilippo Syndrome (MPS-III) Scheie Syndrome (MPS-IS) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Hunter Syndrome (MPS-II) Hurler Syndrome (MPS-IH) Maroteaux-Lamy Syndrome (MPS-VI) Morquio Syndrome (MPS-IV) Sanfilippo Syndrome (MPS-III) Scheie Syndrome (MPS-IS) ### Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII) Autologous(Used by baby) Mucolipidosis II (I-cell Disease) Allogeneic(Used by sibling or family) Mucolipidosis II (I-cell Disease) Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Mucolipidosis II (I-cell Disease) ### Leukodystrophy Disorders Autologous(Used by baby) Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN) Krabbe Disease (Globoid Cell Leukodystrophy) Metachromatic Leukodystrophy Pelizaeus-Merzbacher Disease Allogeneic(Used by sibling or family) Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN) Krabbe Disease (Globoid Cell Leukodystrophy) Metachromatic Leukodystrophy Pelizaeus-Merzbacher Disease Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Adrenoleukodystrophy (ALD) / Adrenomyeloneuropathy (AMN) Krabbe Disease (Globoid Cell Leukodystrophy) Metachromatic Leukodystrophy Pelizaeus-Merzbacher Disease ### Lysosomal Storage Diseases Autologous(Used by baby) Niemann-Pick Disease Sandhoff Disease Wolman Disease Allogeneic(Used by sibling or family) Niemann-Pick Disease Sandhoff Disease Wolman Disease Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Niemann-Pick Disease Sandhoff Disease Wolman Disease ### Inherited Disorders–Other Autologous(Used by baby) Lesch-Nyhan Syndrome Osteopetrosis Allogeneic(Used by sibling or family) Lesch-Nyhan Syndrome Osteopetrosis Diagnosis Autologous (Used by baby) Allogeneic (Used by sibling or family) Lesch-Nyhan Syndrome Osteopetrosis ## **Clinical Trials** Using Stem Cells Newborn stem cells are at the forefront of hundreds of clinical trials across various medical conditions, highlighting their versatility and therapeutic potential. They serve as a primary treatment option in some cases, while in others, they are explored when conventional therapies prove insufficient. These ongoing trials underscore the immense promise and potential that newborn stem cells hold in transforming the landscape of medical treatment and offering hope to patients facing various health challenges. ### Neurological Disorders Using Cord Blood Alzheimer's Disease Autism Cerebral Palsy Dementia Encephalopathy Global Development Delay Hearing Loss (acquired sensorineural) Intraventricular Hemorrhage Neuro-degeneration Parkinson's Disease Spinal Cord Injury Stroke Traumatic Brain Injury Using Cord Tissue Alzheimer's Disease Autism Cerebral Palsy Dementia Encephalopathy Global Development Delay Hearing Loss (acquired sensorineural) Intraventricular Hemorrhage Neuro-degeneration Parkinson's Disease Spinal Cord Injury Stroke Traumatic Brain Injury Using Placental Tissue Alzheimer's Disease Autism Cerebral Palsy Dementia Encephalopathy Global Development Delay Hearing Loss (acquired sensorineural) Intraventricular Hemorrhage Neuro-degeneration Parkinson's Disease Spinal Cord Injury Stroke Traumatic Brain Injury Using Exosomes Alzheimer's Disease Autism Cerebral Palsy Dementia Encephalopathy Global Development Delay Hearing Loss (acquired sensorineural) Intraventricular Hemorrhage Neuro-degeneration Parkinson's Disease Spinal Cord Injury Stroke Traumatic Brain Injury Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Alzheimer's Disease Autism Cerebral Palsy Dementia Encephalopathy Global Development Delay Hearing Loss (acquired sensorineural) Intraventricular Hemorrhage Neuro-degeneration Parkinson's Disease Spinal Cord Injury Stroke Traumatic Brain Injury ### Autoimmune Disorders Using Cord Blood Alopecia Areata Amyotrophic Lateral Sclerosis (ALS) Crohn's Disease Eczema (Atopic Dermatitis) Graft-versus-Host Disease (GvHD) Lupus Multiple Sclerosis Psoriasis Rheumatoid Arthritis Scleroderma Systemic Sclerosis Ulcerative Colitis Using Cord Tissue Alopecia Areata Amyotrophic Lateral Sclerosis (ALS) Crohn's Disease Eczema (Atopic Dermatitis) Graft-versus-Host Disease (GvHD) Lupus Multiple Sclerosis Psoriasis Rheumatoid Arthritis Scleroderma Systemic Sclerosis Ulcerative Colitis Using Placental Tissue Alopecia Areata Amyotrophic Lateral Sclerosis (ALS) Crohn's Disease Eczema (Atopic Dermatitis) Graft-versus-Host Disease (GvHD) Lupus Multiple Sclerosis Psoriasis Rheumatoid Arthritis Scleroderma Systemic Sclerosis Ulcerative Colitis Using Exosomes Alopecia Areata Amyotrophic Lateral Sclerosis (ALS) Crohn's Disease Eczema (Atopic Dermatitis) Graft-versus-Host Disease (GvHD) Lupus Multiple Sclerosis Psoriasis Rheumatoid Arthritis Scleroderma Systemic Sclerosis Ulcerative Colitis Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Alopecia Areata Amyotrophic Lateral Sclerosis (ALS) Crohn's Disease Eczema (Atopic Dermatitis) Graft-versus-Host Disease (GvHD) Lupus Multiple Sclerosis Psoriasis Rheumatoid Arthritis Scleroderma Systemic Sclerosis Ulcerative Colitis ### Cardiovascular Using Cord Blood Acute Myocardial Infarction (Heart Attack) Cardiomyopathy Critical Limb Ischemia (CLI) Heart Failure Peripheral Arterial Disease (PAD) Surgery for Congenital Heart Defects Using Cord Tissue Acute Myocardial Infarction (Heart Attack) Cardiomyopathy Critical Limb Ischemia (CLI) Heart Failure Peripheral Arterial Disease (PAD) Surgery for Congenital Heart Defects Using Placental Tissue Acute Myocardial Infarction (Heart Attack) Cardiomyopathy Critical Limb Ischemia (CLI) Heart Failure Peripheral Arterial Disease (PAD) Surgery for Congenital Heart Defects Using Exosomes Acute Myocardial Infarction (Heart Attack) Cardiomyopathy Critical Limb Ischemia (CLI) Heart Failure Peripheral Arterial Disease (PAD) Surgery for Congenital Heart Defects Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Acute Myocardial Infarction (Heart Attack) Cardiomyopathy Critical Limb Ischemia (CLI) Heart Failure Peripheral Arterial Disease (PAD) Surgery for Congenital Heart Defects ### Diabetic Using Cord Blood Diabetes, Type 1 (Auto-Immune) Diabetes, Type 2 Diabetic Foot Ulcer Diabetic Peripheral Neuropathy Using Cord Tissue Diabetes, Type 1 (Auto-Immune) Diabetes, Type 2 Diabetic Foot Ulcer Diabetic Peripheral Neuropathy Using Placental Tissue Diabetes, Type 1 (Auto-Immune) Diabetes, Type 2 Diabetic Foot Ulcer Diabetic Peripheral Neuropathy Using Exosomes Diabetes, Type 1 (Auto-Immune) Diabetes, Type 2 Diabetic Foot Ulcer Diabetic Peripheral Neuropathy Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Diabetes, Type 1 (Auto-Immune) Diabetes, Type 2 Diabetic Foot Ulcer Diabetic Peripheral Neuropathy ### Genetic and/or Metabolic Disorders Using Cord Blood Aging Frailty Duchenne Muscular Dystrophy Epidermolysis Bullosa Hereditary Ataxia Lysosomal Storage Diseases Metabolic Syndrome Severe Combined Immunodeficiency Spinal Muscular Atrophy Tay-Sachs Disease Using Cord Tissue Aging Frailty Duchenne Muscular Dystrophy Epidermolysis Bullosa Hereditary Ataxia Lysosomal Storage Diseases Metabolic Syndrome Severe Combined Immunodeficiency Spinal Muscular Atrophy Tay-Sachs Disease Using Placental Tissue Aging Frailty Duchenne Muscular Dystrophy Epidermolysis Bullosa Hereditary Ataxia Lysosomal Storage Diseases Metabolic Syndrome Severe Combined Immunodeficiency Spinal Muscular Atrophy Tay-Sachs Disease Using Exosomes Aging Frailty Duchenne Muscular Dystrophy Epidermolysis Bullosa Hereditary Ataxia Lysosomal Storage Diseases Metabolic Syndrome Severe Combined Immunodeficiency Spinal Muscular Atrophy Tay-Sachs Disease Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Aging Frailty Duchenne Muscular Dystrophy Epidermolysis Bullosa Hereditary Ataxia Lysosomal Storage Diseases Metabolic Syndrome Severe Combined Immunodeficiency Spinal Muscular Atrophy Tay-Sachs Disease ### Orthopedic Using Cord Blood Ankylosing Spondylitis Cartilage Injury Cleft Palate Repair Non-Union Fractures Osteoarthritis Osteochondral Lesion Spinal Fusion Surgery Using Cord Tissue Ankylosing Spondylitis Cartilage Injury Cleft Palate Repair Non-Union Fractures Osteoarthritis Osteochondral Lesion Spinal Fusion Surgery Using Placental Tissue Ankylosing Spondylitis Cartilage Injury Cleft Palate Repair Non-Union Fractures Osteoarthritis Osteochondral Lesion Spinal Fusion Surgery Using Exosomes Ankylosing Spondylitis Cartilage Injury Cleft Palate Repair Non-Union Fractures Osteoarthritis Osteochondral Lesion Spinal Fusion Surgery Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Ankylosing Spondylitis Cartilage Injury Cleft Palate Repair Non-Union Fractures Osteoarthritis Osteochondral Lesion Spinal Fusion Surgery ### Other Using Cord Blood Acute Respiratory Distress Syndrome (ARDS) Blood Coagulation Broncopulmonary Dysplasia (BPD) Chronic Low Bank Pain Erectile Dysfunction Eye Diseases Fistula HIV Inflammatory Diseases Kidney Failure Liver Cirrhosis Liver Failure Lung Cancer Metastatic Melanoma Pancreatic Cancer Peyronie's Disease Platelet Function Premature Ovarian Failure Uterine Scars Wounds Using Cord Tissue Acute Respiratory Distress Syndrome (ARDS) Blood Coagulation Broncopulmonary Dysplasia (BPD) Chronic Low Bank Pain Erectile Dysfunction Eye Diseases Fistula HIV Inflammatory Diseases Kidney Failure Liver Cirrhosis Liver Failure Lung Cancer Metastatic Melanoma Pancreatic Cancer Peyronie's Disease Platelet Function Premature Ovarian Failure Uterine Scars Wounds Using Placental Tissue Acute Respiratory Distress Syndrome (ARDS) Blood Coagulation Broncopulmonary Dysplasia (BPD) Chronic Low Bank Pain Erectile Dysfunction Eye Diseases Fistula HIV Inflammatory Diseases Kidney Failure Liver Cirrhosis Liver Failure Lung Cancer Metastatic Melanoma Pancreatic Cancer Peyronie's Disease Platelet Function Premature Ovarian Failure Uterine Scars Wounds Using Exosomes Acute Respiratory Distress Syndrome (ARDS) Blood Coagulation Broncopulmonary Dysplasia (BPD) Chronic Low Bank Pain Erectile Dysfunction Eye Diseases Fistula HIV Inflammatory Diseases Kidney Failure Liver Cirrhosis Liver Failure Lung Cancer Metastatic Melanoma Pancreatic Cancer Peyronie's Disease Platelet Function Premature Ovarian Failure Uterine Scars Wounds Diagnosis Using Cord Blood Using Cord Tissue Using Placental Tissue Using Exosomes Acute Respiratory Distress Syndrome (ARDS) Blood Coagulation Broncopulmonary Dysplasia (BPD) Chronic Low Bank Pain Erectile Dysfunction Eye Diseases Fistula HIV Inflammatory Diseases Kidney Failure Liver Cirrhosis Liver Failure Lung Cancer Metastatic Melanoma Pancreatic Cancer Peyronie's Disease Platelet Function Premature Ovarian Failure Uterine Scars Wounds