What are Exosomes?

Decades of research have yielded evidence for the role of exosomes in intercellular communication. In fact, pre-clinical research has shown that exosomes may regulate immune responses, wound healing, and cell growth & development. Today, there are currently no FDA-approved treatments, but researchers and scientists are studying these tiny vesicles for more than 100 clinical trials researching numerous applications for exosomes.

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What are Exosomes?

Exosomes are tiny, extracellular vesicles that act as messengers by shuttling cellular components to other cells. They initiate cell-to-cell communication. 

 

Exosomes are 30-150 nanometers in diameter. They are filled with a rich variety of proteins (Signaling, RNA, and DNA) and lipids. The composition of the exosome depends strongly on the type of cell the exosome originates from.

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Why are Proteins and Lipids So Important?

Proteins and lipids are the building blocks of human life. Every cell in the human body contains proteins and lipids. They play an important role in cellular processes. Proteins help repair cells and make new ones. Lipids contribute to the structural development, metabolism, and energy production inside a cell.
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Americord CryoMaxx™ Exosome Processing

Americord’s CryoMaxx™ Exosome Processing unlocks the future potential of mom and baby’s cord blood exosomes. The process uses a minimal manipulation process that enables lab technicians to isolate and extract exosomes from the cord blood. The exosomes are then cryopreserved, which ensures the potential for clinical research or future treatments.

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Questions About Exosome Banking?

Our Stem Cell Consultants are here to help. Chat now or schedule a free consultation for one on one guidance to answer all of yours questions.

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Clinical Trials Using Exosomes

There are no FDA-approved treatments using exosomes. However, there are hundreds of clinical trials researching numerous applications for exosomes.

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Cancers

Pancreatic Cancer 

Lung Cancer 

Metastatic Melanoma

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Blood Disorders

Platelet Function 

Blood Coagulation 

Inflammatory Diseases

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And Much More

Neuro-degeneration 

Chronic low back pain 

Dementia

Questions About Exosomes

Exosomes are small, membrane-bound vesicles that are produced and released by cells as a way to communicate with other cells. These vesicles play a role in intercellular communication by transporting various molecules, such as proteins, lipids, and nucleic acids, between cells.

Exosomes are isolated and concentrated from the plasma portion of cord blood using our proprietary CryoMaxx™ Process. The process uses a minimal manipulation process that enables lab technicians to isolate and extract exosomes from the cord blood. The exosomes are then cryopreserved, which ensures the potential for clinical research or future treatments.

No. There are no FDA approved treatments using exosomes. However, there more than 100 clinical trials researching numerous applications for exosomes. Much like cord tissue and placenta tissue, these must be used in clinical trials.

There are no FDA-approved exosome treatments or products. Any marketing of exosomes products as biologic drugs intended for use in humans is illegal. However, there are numerous FDA-monitored clinical trials investigating the potential use of exosomes as a therapeutic treatment. Americord offers exosome banking for potential use in clinical research.

Exosomes are not cells nor are they living organisms. Therefore, exosomes can not be expanded. Exosome processing isolates and concentrates whatever exosomes are already present in the cord blood.

Americord acknowledges that exosomes are not FDA-approved for use in treatments or products. Americord does not claim exosomes have any current therapeutic benefit. The client understands that they bank their child’s exosomes for use in clinical trials and research which may provide utility in the future.