Cord Tissue with Americord CryoMaxx™ Processing
What is The Umbilical Cord?
The umbilical cord plays an important role during pregnancy. It is responsible for delivering nutrients and oxygen to the baby, and removing waste material. The cord is a tube-like structure that connects the baby to the mother through the placenta.
The umbilical cord is so much more than a highway to good health while the baby is in the womb!
What Cells Are Found in The Umbilical Cord?
- Mesenchymal stem cells (MSCs)
- Growth factors
- Cytokines
- And other important cells
What Are Mesenchymal Stem Cells?
The umbilical cord contains mesenchymal stem cells (MSCs), a different type of stem cell not found in cord blood. These MSCs are found in Wharton’s jelly and are multipotent cells. This means they can develop into various cell types which lead to the formation of skin, bone, cartilage, nerve, and muscle tissues.
Source: Chicago BioMedical Consortium
Clinical Trials Using Cord Tissue
Cord derived MSCs are currently being studied in 100’s of clinical trials1:
- ALS
- Alzheimer’s
- Arthritis
- Autism
- Cerebral Palsy
- Chrone’s Disease
- Diabetes
- Liver Cirrhosis
- Multiple Sclerosis
- Parkinson’s
Using Cord Tissue Stem Cells in Surgery
Cord tissue, consisting of cells, growth factors, and cytokines, is currently being studied in a number of clinical trials for surgical applications2-7:
- Cartilage Repair
- General Surgery
- Orthopedic Surgery
- Tendon Repair
- Urology
The Difference Between Cord Blood and Cord Tissue Banking
While cord blood banking collects the hematopoietic stem cells (HSCs) found in the cord blood, cord tissue banking preserves the umbilical cord which contains various cell types including MSCs, growth factors, and cytokines.
Is Cord Tissue Banking Worth it?: Americord CryoMaxx™ Cord Tissue Processing
Many blood banks focus only on the MSCs and pre-process them prior to cryopreservation, limiting future treatment options. Americord continues to stay up-to-date with new advances in regenerative medicine and has developed an innovative, new processing method: Americord CryoMaxx™.
Americord’s CryoMaxx™ processing method unlocks the full potential of umbilical cord tissue. The process uses a minimal manipulation method to enable the cord tissue to retain its inherent multipotent cells, growth factors, and cytokines.
The cord tissue is then cryopreserved as a membrane containing living cells and bioactive factors and stored in multiple vials, which ensures the potential for multiple uses or applications. The cryopreserved cord tissue can be used for surgical applications or be processed in the future using the latest cell isolation techniques. Americord’s CryoMaxx™ processing brings peace of mind to families and gives doctors and patients the flexibility to use the cord tissue stem cells for a wide range of therapeutic applications.
References:
- https://stemcellres.biomedcentral.com/articles/10.1186/s13287-021-02222-y
- https://clinicaltrials.gov/ct2/show/NCT04263025
- https://clinicaltrials.gov/ct2/show/NCT03084068?term=umbilical+cord+allograft&draw=2&rank=1
- https://clinicaltrials.gov/ct2/show/NCT05081232?term=umbilical+cord+allograft&draw=2&rank=9
- https://clinicaltrials.gov/ct2/show/NCT03337243?term=umbilical+cord+allograft&draw=2&rank=15
- https://clinicaltrials.gov/ct2/show/NCT03113786?term=amniox&draw=2&rank=3
- https://clinicaltrials.gov/ct2/show/NCT02719288?term=amniox&draw=2&rank=5
