What is Cord Tissue Banking?

The cord tissue is rich in powerful healing stem cells and contains the cells and signals required for regenerative medicine applications. It contains mesenchymal stem cells (MSCs), but also other types of stem cells including epithelial and endothelial stem cells. MSCs are multipotent stem cells capable of differentiating into a number of different cell and tissue types. The cord tissue also contains growth factors and cytokines. Growth factors are signaling molecules that regulate cell growth and tissue regeneration, while cytokines are signaling molecules that regulate inflammation.

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What is the Umbilical Cord?

The umbilical cord plays an important role during pregnancy. It is responsible for delivering nutrients and oxygen to the baby and removing waste material. The cord is a tube-like structure that connects the baby to the mother through the placenta. The umbilical cord consists of the cord lining and the Wharton's Jelly which provides cushioning and surrounds the two umbilical arteries and one umbilical vein.
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What are Mesenchymal Stem Cells?

Wharton's Jelly is found in the umbilical cord. It is a rich source of mesenchymal stem cells (MSCs). MSCs are multipotent stem cells capable of differentiating into different cell types. These powerful cells can lead to the regeneration of skin, bone, cartilage, nerve, muscle tissues, and more.
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The Difference Between Cord Tissue and Cord Blood Banking

The primary intent of cord blood banking is to isolate and cryogenically preserve hematopoietic stem cells (HSCs) found in cord blood. Whereas the primary intent of cord tissue banking is to process and cryogenically preserve the cord tissue which contains mesenchymal stem cells (MSCs), growth factors, and cytokines. 

 

Cord blood HSCs are FDA-approved to treat over 80 blood-related diseases and disorders. Treatments include various types of blood cancers and disorders and metabolic and immune disorders. In addition, there are 100s of ongoing clinical trials researching treatment options using HSCs for neurological disorders, traumatic brain injuries, cardiovascular disease, and autoimmune disorders. 

 

Cord tissue is more versatile due to it containing MSCs, growth factors, and cytokines. It has potential applications that are distinct from applications using cord blood HSCs. There are 100s of clinical trials researching treatment options for Alzheimer’s disease, diabetes, Parkinson’s disease, and orthopedic diseases and disorders. 

 

Together, cord blood and cord tissue could be the future of regenerative medicine. Many expectant parents choose to preserve both to provide the widest potential scope of treatment options for the future.

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Questions About Cord Tissue Banking?

Our Stem Cell Consultants are here to help. Chat now or schedule a free consultation for one on one guidance to answer all of yours questions.

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Americord CryoMaxx™ Cord Tissue Processing

Many blood banks focus only on preserving the MSCs and pre-process them prior to cryopreservation, limiting future treatment options. Americord continues to stay up-to-date with new advances in regenerative medicine and has developed an innovative, new processing method: Americord CryoMaxx™. 

 

Americord’s CryoMaxx™ processing method unlocks the full potential of umbilical cord tissue. The process uses a minimal manipulation method to enable the cord tissue to retain its inherent multipotent cells, growth factors, and cytokines. The cord tissue is cryopreserved as a membrane. It contains living cells and bioactive factors and is stored in multiple vials, which ensures the potential for multiple uses or applications. The cryopreserved cord tissue can be used for surgical applications or be processed in the future using the latest cell isolation techniques. 

 

Americord’s CryoMaxx™ processing brings peace of mind to families and gives doctors and patients the flexibility to use the cord tissue stem cells for a wide range of therapeutic applications.

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Clinical Trials Using Cord Tissue

Cord derived MSCs are currently being studied in hundreds of clinical trials.

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Non-Blood Related Disorders

Autism 

Cerebral Palsy 

Liver Cirrhosis 

Pulmonary Inflammation and Infection 

Graft Versus Host Disease

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Autoimmune Disorders

Lupus 

Psoriasis 

Rheumatoid Arthritis 

Refractory Immune Thrombocytopenia 

Cirrhosis

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Degenerative Conditions

Multiple Sclerosis 

Parkinson’s 

Vascular Dementia 

Eye Conditions

Clinical Trials Using Cord Tissue in Surgery

Cord tissue, consisting of cells, growth factors, and cytokines, is currently being studied in a number of clinical trials for surgical applications. Clinical trials in progress are evaluating the power of cord tissue producing less surgical scarring and encouraging improved healing.

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Orthopedic Conditions

General Surgery 

Osteoarthritis 

Arthroscopic Rotator Cuff Repair 

Lumbar Discogenic Pain 

Gonarthrosis (Whanko)

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Wounds & Injuries

Caesarean Section Scars 

Tendon Repair 

Spinal Cord Injuries 

Brain Injuries 

Nerve Injuries

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The Future is Bright

Hundreds of new clinical trials using cord tissue for surgical purposes are being conducted each year. The future has never been more exciting.

Questions About Cord Tissue

Cord tissue contains MSCs, which are a key component in regenerative medicine. These stem cells have the potential to repair and regenerate damaged tissues and organs, offering hope for treating a wide range of medical conditions. Regenerative medicine applications include orthopedic issues, heart disease, spinal cord injuries, and more.

Our commitment to excellence is evident in our proprietary and cutting-edge processing method, CryoMaxx™ Processing. This revolutionary approach is designed to minimize manipulation, allowing the cord tissue to retain its innate multipotent cells, growth factors, and cytokines.

Through CryoMaxx™ Processing, we unlock the extraordinary healing potential inherent within the cord tissue. This advanced technique preserves the essential components that make cord tissue an invaluable resource for regenerative medicine, ensuring that it maintains its full therapeutic efficacy for potential future applications.

We employ a meticulous process to extract and isolate the Mesenchymal Stem Cells (MSCs) from the cord tissue. These invaluable cells undergo thorough viability testing to ensure their health and effectiveness. Once verified, they are preserved through cryogenic freezing in state-of-the-art vapor nitrogen tanks.

What sets our approach apart is the storage method. The cord tissue is carefully divided into multiple vials, creating the potential for numerous applications and uses. This strategy maximizes the utility of the preserved cord tissue, allowing for flexibility and multiple opportunities to harness its regenerative and therapeutic potential.

Cord tissue stem cells, specifically mesenchymal stem cells (MSCs), are indeed making significant strides in the field of regenerative medicine. They hold immense promise for a wide range of medical conditions and therapies and are currently being used in hundreds of clinical trials including Cerebral Palsy, surgical applications, and more.

Your baby's cord tissue holds the potential to benefit both immediate family members, such as parents and siblings, as well as second-degree family members, like grandparents. This means that not only can it provide essential support to your closest loved ones, but also offer a valuable resource for relatives beyond your immediate family circle.

Banking both cord blood and cord tissue presents an exceptional opportunity to secure a diverse range of life-saving stem cells and regenerative resources for your baby's future. These perinatal tissues, rich in multi-potent stem cells, growth factors, cytokines, and extracellular matrix proteins, hold the potential to treat over eighty medical conditions and are actively studied in numerous clinical trials.

Moreover, the combination of cord blood hematopoietic stem cells and cord tissue mesenchymal stem cells offers a synergistic approach with the potential for therapeutic benefits surpassing today's treatments. Making the choice to bank both cord blood and cord tissue is a forward-thinking investment in your child's health, with opportunities for groundbreaking clinical applications today and in the future.