New mom holding newborn with nurse smiling

The First 48 Hours: What Really Happens at the Hospital After Delivery

Key Takeaways

The first 48 hours after delivery involve critical health screenings for newborns, including Apgar scores and metabolic tests. Mothers receive monitoring for recovery and pain management while establishing breastfeeding. This window is the only time to collect life-saving newborn stem cells, a process that integrates seamlessly with your hospital birth plan.

The first 48 hours after delivery are filled with essential care for both you and your baby. Here’s what happens:

  • Mom’s Recovery: Nurses monitor bleeding, uterine contractions, and vital signs. Pain relief includes ibuprofen, acetaminophen, or ice packs. For C-sections, incision care and early movement are key.
  • Baby’s Care: Your newborn undergoes Apgar scoring, a Vitamin K shot, antibiotic eye ointment, and health screenings for hearing, metabolic conditions, and jaundice. Skin-to-skin contact and breastfeeding are prioritized. This is also the ideal time to discuss cord blood banking benefits with your care team.
  • Tests and Vaccines: Metabolic screening (heel prick), pulse oximetry (oxygen levels), and the first Hepatitis B vaccine are standard.
  • Discharge Prep: Before leaving, both mom and baby must pass final exams, including car seat checks and safe sleep guidance.

Planning ahead — packing your hospital bag early, selecting a pediatrician, and staying healthy after childbirth — can make this transition smoother.

Hour 0-1: Immediate Care After Delivery

Baby's First Health Checks: Apgar Score and Initial Assessment

Right after birth, your baby undergoes an Apgar score test — a quick evaluation that looks at five key signs: heart rate, breathing effort, muscle tone, reflex response, and skin color1. Each category is scored from 0 to 2, with a maximum total of 10. This test is repeated five minutes later to see how well your baby is adapting to life outside the womb.

Apgar Metric 0 Points 1 Point 2 Points
Activity (Muscle Tone) Limp; floppy Some flexion Active; moving
Pulse (Heart Rate) Absent Below 100 bpm Over 100 bpm
Grimace (Reflexes) No response Grimace Sneeze, cough, or pull away
Appearance (Skin Color) Blue-gray; pale Normal color except extremities Normal color all over
Respiration (Breathing) Absent Slow; irregular Good; crying

Scores between 7 and 10 are normal, and most babies reach this range by five minutes. A score of 4 to 6 may mean your baby needs extra help, like oxygen or rescue breathing, while a score of 3 or below signals the need for immediate medical attention.

Other health checks include weighing, measuring length, and checking head circumference. Your baby will also receive a Vitamin K injection to support proper blood clotting and antibiotic eye ointment to prevent infections. After the umbilical cord is clamped and cut — at which point you may choose to bank cord blood, tissue, and placenta tissue — the stump is examined for stability.

Mother's Immediate Postpartum Care

Nurses check to ensure your uterus is firming up and shrinking to prevent heavy bleeding. If you had a vaginal tear, your doctor will use dissolvable stitches. For C-section deliveries, the incision is closed with stitches, staples, or surgical glue. This initial recovery period usually lasts around two hours in the Labor and Delivery Unit before you’re moved to a postpartum room.

Skin-to-Skin Contact and First Breastfeeding Attempt

The first hour after birth is the "Golden Hour". Immediate skin-to-skin contact helps regulate the baby's temperature and triggers oxytocin in your body, aiding in placenta delivery2.

Facilitate immediate and uninterrupted skin‐to‐skin contact and support mothers to initiate breastfeeding as soon as possible after birth. - WHO/UNICEF

Hour 1-24: Newborn Tests and Early Recovery

Standard Newborn Health Screenings

Key tests include the metabolic screening (heel prick) to check for conditions like PKU and sickle cell disease3. Your baby will also undergo a hearing screening, receive the first Hepatitis B vaccine, and have pulse oximetry performed to screen for congenital heart defects.

A blood test is the only way to find out about these metabolic problems. If found right away, serious problems like developmental disabilities, organ damage, blindness, and even death might be prevented. - U.S. Department of Health & Human Services

Hour 24-48: Final Checks and Discharge Preparation

Discharge Process and Final Medical Exams

Before heading home, the hospital verifies you have a properly installed infant car seat and reviews safe sleep practices to prevent SIDS.

Newborn Stem Cell Banking with Americord Registry

The first 48 hours present a unique opportunity: preserving your baby’s stem cells for potential future use.

Cord Blood and Tissue Collection Process

Americord’s collection process works seamlessly alongside delayed cord clamping. We collect cord blood, cord tissue, and placental tissue using proprietary methods designed to be non-intrusive.

Americord Registry's CryoMaxx™ Processing Technology

Americord Registry utilizes CryoMaxx™ technology to preserve the natural state and potency of stem cells. We offer a $110,000 engraftment guarantee to give families peace of mind.

Americord Registry Plan Options

Americord provides five flexible plans, each including unique stem cell banking options. Please note that pricing is subject to change, and annual fees apply (in some cases). For the most up-to-date information, visit our pricing page.

Conclusion: Preparing for the First 48 Hours

Start by packing your hospital bag early, including your Americord Collection Kit. Planning ahead allows you to focus on bonding while ensuring your baby’s future health resources are secured.

FAQs

What health checks does a newborn go through in the first 48 hours after birth?

Newborns receive a full physical exam, Apgar testing, hearing screenings, and metabolic blood tests to ensure a healthy start.


References

  1. American Academy of Pediatrics. Apgar Scores. https://www.aap.org
  2. World Health Organization. Postnatal care of the mother and newborn. https://www.who.int
  3. U.S. Department of Health & Human Services. Newborn Screening. https://www.hrsa.gov